Alteration of Fermentative Metabolism Enhances Mucor circinelloides Virulence
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چکیده
منابع مشابه
Sporangiospore Size Dimorphism Is Linked to Virulence of Mucor circinelloides
Mucor circinelloides is a zygomycete fungus and an emerging opportunistic pathogen in immunocompromised patients, especially transplant recipients and in some cases otherwise healthy individuals. We have discovered a novel example of size dimorphism linked to virulence. M. circinelloides is a heterothallic fungus: (+) sex allele encodes SexP and (-) sex allele SexM, both of which are HMG domain...
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Many pathogenic fungi are dimorphic and switch between yeast and filamentous states. This switch alters host-microbe interactions and is critical for pathogenicity. However, in zygomycetes, whether dimorphism contributes to virulence is a central unanswered question. The pathogenic zygomycete Mucor circinelloides exhibits hyphal growth in aerobic conditions but switches to multi-budded yeast gr...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2020
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.00434-19